Now you're throwing a monkey into the wrench with the female shooter scenario.

I think the full house 357 load recoiled sharper than a defensive 45acp round where it feels like a heavy push.
I have no problem recommending a woman shooter to use +P .38spl rounds if she has problems with .357. Either 158gr. +P or 135gr. +P would do the trick. For anybody, 6 hits with a "lowly" .38 is better than a bunch of misses with .357 or .45.
Another thing to think about, if the shooter (female or male) is of the small frame variety, using a heavy gun like the 625 may not work so well. It's over 40 ounce chunk of steel that the shooter has to manipulate in time of stress. A compromise with slightly lighter gun may get better results.
I shoot better with a 2" model 10 than the 625 Mountain Gun despite the shorter barrel.
Good luck.